SCHEMBL6300495

SCHEMBL6300495

O=C1C=CC(=O)C(c2ccc([N+](=O)[O-])c3c2ccc2cccc([N+](=O)[O-])c23)=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.40
ALDH1A1 P00352 3/20 0.38
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
CES1 P23141 1/20 0.38
AURKA O14965 1/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
PTPN1 P18031 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915319 0.82 ALDH1A1 (0.38) TYMSALDH1A1BCHEACHECES1
SCHEMBL309868 0.81 MAOA (0.42) ALDH1A1BCHEACHECES1MEN1
Benzoquinone SCHEMBL27576817 0.80 MAOA (0.41) ALDH1A1BCHEACHECES1MEN1
SCHEMBL9239563 0.78 TDP1 (0.56) ALDH1A1AURKAMEN1KMT2ANPC1
SCHEMBL1966364 0.77 MAOA (0.41) TYMSALDH1A1BCHEACHECES1
SCHEMBL2700202 0.72 HPRT1 (0.51) ALDH1A1CES1MEN1KMT2APTPN1
SCHEMBL499148 0.70 ALDH1A1 (0.41) TYMSALDH1A1BCHEACHECES1
SCHEMBL51777 0.69 ALDH1A1 (0.54) ALDH1A1CES1MEN1KMT2APTPN1
SCHEMBL28569068 0.69 ALDH1A1 (0.54) ALDH1A1CES1MEN1KMT2APTPN1
SCHEMBL2380017 0.69 ALDH1A1 (0.54) ALDH1A1CES1MEN1KMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846956-B2 Triarylmethane dyes BASF AKTIENGESELLSCHAFT (DE) 2005-01-25 US disclosed
US-20030181740-A1 Triarylmethane dyes BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 US disclosed
US-4340540-A NITROGEN OXIDES OXIDATION CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
US-4330476-A CONDENSATION OF AROMATIC ALDEHYDE WITH AROMATIC AMINE FOLLOWED BY OXIDATION BAYER AKTIENGESELLSCHAFT (DE) 1982-05-18 US disclosed
US-4318859-A CONTAINING CARBONIUM GROUPS BY CATALYTIC OXIDATION BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed