Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630231 | 0.94 | EPHX2 (0.44) | MAPTALDH1A1GAAKDM4EL3MBTL1 | |
| SCHEMBL630495 | 0.93 | POLB (0.44) | KCNQ1MAPTALDH1A1GAAKDM4E | |
| SCHEMBL631414 | 0.92 | POLB (0.42) | KCNQ1MAPTALDH1A1GAAKDM4E | |
| SCHEMBL630210 | 0.91 | KCNQ1 (0.54) | KCNQ1HCRTR1HCRTR2CCNCCDK8 | |
| SCHEMBL630680 | 0.89 | KCNQ1 (0.48) | KCNQ1HCRTR1HCRTR2MAPTALDH1A1 | |
| SCHEMBL631050 | 0.88 | KCNQ1 (0.47) | KCNQ1HCRTR1HCRTR2MAPTALDH1A1 | |
| SCHEMBL630823 | 0.84 | KCNQ1 (0.49) | KCNQ1HCRTR1HCRTR2MAPTALDH1A1 | |
| SCHEMBL1380078 | 0.84 | POLB (0.53) | KCNQ1HCRTR1HCRTR2MAPTALDH1A1 | |
| SCHEMBL630103 | 0.84 | POLB (0.53) | KCNQ1HCRTR1HCRTR2MAPTALDH1A1 | |
| SCHEMBL630671 | 0.84 | POLB (0.46) | KCNQ1HCRTR1HCRTR2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |