Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631181 | 0.92 | LMNA (0.44) | POLBLMNACHRM2CHRM3MAPT | |
| SCHEMBL630349 | 0.90 | POLB (0.54) | POLBLMNACHRM2CHRM3MAPT | |
| SCHEMBL1382765 | 0.90 | POLB (0.54) | POLBLMNACHRM2CHRM3MAPT | |
| SCHEMBL630495 | 0.89 | POLB (0.44) | POLBLMNACHRM2CHRM3MAPT | |
| SCHEMBL630680 | 0.85 | KCNQ1 (0.48) | POLBMAPTKCNQ1KMT2AHCRTR1 | |
| SCHEMBL630055 | 0.84 | KCNQ1 (0.47) | POLBLMNAMAPTKCNQ1KMT2A | |
| SCHEMBL631034 | 0.83 | KCNQ1 (0.44) | POLBKCNQ1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL630231 | 0.82 | EPHX2 (0.44) | POLBLMNAMAPTKMT2ABDKRB1 | |
| SCHEMBL630614 | 0.82 | POLB (0.44) | POLBCHRM2CHRM3KCNQ1KMT2A | |
| SCHEMBL13206969 | 0.82 | LMNA (0.53) | POLBLMNAKCNQ1KMT2AHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |