Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6294978 | 0.95 | F2 (0.49) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6295817 | 0.91 | PLA2G7 (0.46) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7154640 | 0.90 | PLA2G7 (0.46) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7158686 | 0.90 | F2 (0.45) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6377229 | 0.89 | AKR1C3 (0.52) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL8475188 | 0.89 | PRSS1 (0.44) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6295821 | 0.87 | PLA2G7 (0.44) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6300757 | 0.87 | PLA2G7 (0.44) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL6294964 | 0.87 | F2 (0.48) | PRSS1PRSS2PRSS3ST14F2 | |
| Trifluoroacetic Acid SCHEMBL7157101 | 0.87 | PLA2G7 (0.44) | PRSS1PRSS2PRSS3ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |