SCHEMBL6300786

SCHEMBL6300786

[CH2]C(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 18/20 0.77
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
CXCR3 P49682 2/20 0.66
PTGES O14684 2/20 0.63
TAS2R8 Q9NYW2 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1278616 0.87 TAS2R14 (1.00) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL1278788 0.86 TAS2R14 (0.97) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL6976163 0.84 TAS2R14 (0.77) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL6300788 0.84 TAS2R14 (0.77) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL3814018 0.82 TAS2R14 (0.73) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL984791 0.81 TAS2R14 (0.71) TAS2R14MEN1KMT2ACXCR3
SCHEMBL1279120 0.81 TAS2R14 (1.00) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL1168758 0.80 TAS2R14 (1.00) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL1279324 0.80 TAS2R14 (1.00) TAS2R14MEN1KMT2ACXCR3PTGES
SCHEMBL1279183 0.80 TAS2R14 (1.00) TAS2R14MEN1KMT2ACXCR3PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6869968-B1 Such as 3-(4-fluorophenyl)-4-(4-methysulphonylphenyl)-2-(3H)-oxazolone; for treating colorectal cancer, fevers, and inflammation ALLMIRALL PRODESFARMA S.A. (ES) 2005-03-22 US disclosed