Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | NMBR | P28336 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629890 | 0.80 | HDAC2 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1383357 | 0.80 | HDAC2 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL630909 | 0.74 | MMP9 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1382775 | 0.74 | MMP9 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL631494 | 0.74 | F2 (0.48) | F2SMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL631775 | 0.68 | LMNA (0.47) | SMN1; SMN2MAPTMMP2MMP3MMP9 | |
| SCHEMBL7250939 | 0.67 | HDAC8 (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8257252 | 0.67 | NMBR (0.71) | NMBRSMN1; SMN2MAPTCA2MMP2 | |
| SCHEMBL12706375 | 0.65 | NMBR (0.75) | NMBRSMN1; SMN2MAPTCA2MMP2 | |
| SCHEMBL1385938 | 0.65 | F2 (0.51) | F2SMN1; SMN2MAPTMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |