Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631775 | 0.90 | LMNA (0.47) | KCNA5KCNH2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1380411 | 0.87 | F2 (0.51) | F2KCNA5KCNH2MEN1KMT2A | |
| SCHEMBL1385938 | 0.87 | F2 (0.51) | F2KCNA5KCNH2MEN1KMT2A | |
| SCHEMBL630602 | 0.83 | SNCA (0.40) | KCNA5KCNH2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL630918 | 0.81 | FKBP1A (0.45) | MEN1KMT2AMAPTLMNADPP4 | |
| SCHEMBL630182 | 0.78 | LMNA (0.44) | KCNA5KCNH2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1383977 | 0.77 | KMT2A (0.50) | MEN1KMT2ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL1384829 | 0.77 | KMT2A (0.50) | MEN1KMT2ASMN1; SMN2MAPTUSP2 | |
| SCHEMBL630176 | 0.74 | HDAC3 (0.45) | F2SMN1; SMN2MAPTMMP2MMP9 | |
| SCHEMBL629890 | 0.72 | HDAC2 (0.48) | F2MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |