Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631494 | 0.90 | F2 (0.48) | LMNAKMT2AMEN1PKMMAPT | |
| SCHEMBL630182 | 0.86 | LMNA (0.44) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL630918 | 0.86 | FKBP1A (0.45) | LMNAKMT2AMEN1MAPTITGB2 | |
| SCHEMBL1384829 | 0.86 | KMT2A (0.50) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL1383977 | 0.86 | KMT2A (0.50) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL630602 | 0.85 | SNCA (0.40) | LMNAALDH1A1KMT2AMEN1PKM | |
| SCHEMBL630786 | 0.83 | TDP1 (0.46) | LMNAALDH1A1PKM | |
| SCHEMBL630767 | 0.81 | ITGB1 (0.46) | LMNAALDH1A1PKMMAPT | |
| SCHEMBL631469 | 0.80 | ALDH1A1 (0.44) | LMNAALDH1A1PKMMAPTSMN1; SMN2 | |
| SCHEMBL631343 | 0.79 | PKM (0.43) | LMNAALDH1A1PKMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |