Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926394 | 0.84 | KDM4E (0.46) | HPGDALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL4494269 | 0.80 | ALDH1A1 (0.47) | HPGDCHRNA7ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6847297 | 0.77 | ALDH1A1 (0.34) | HPGDALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL6847217 | 0.77 | KMT2A (0.40) | HPGDALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL11572426 | 0.77 | ALDH1A1 (0.42) | HPGDCHRNA7ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27480933 | 0.73 | LOXL2 (0.36) | — | |
| SCHEMBL8055688 | 0.72 | ALDH1A1 (0.50) | HPGDCHRNA7ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6308505 | 0.71 | HPGD (0.49) | HPGDALDH1A1KDM4EMAPK1LMNA | |
| SCHEMBL27761337 | 0.70 | KCNH2 (0.51) | HPGDALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL28926381 | 0.70 | CYP19A1 (0.49) | HPGDALDH1A1KDM4EMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | disclosed |