Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926373 | 0.82 | MAOB (0.39) | KMT2AMAPTTHRBSMN1; SMN2HPGD | |
| SCHEMBL6847297 | 0.81 | ALDH1A1 (0.34) | MAPTSMN1; SMN2HPGDALDH1A1HTT | |
| SCHEMBL11572426 | 0.81 | ALDH1A1 (0.42) | SMN1; SMN2HPGDALDH1A1KDM4EGAA | |
| SCHEMBL6301892 | 0.77 | HPGD (0.44) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL27480933 | 0.77 | LOXL2 (0.36) | KMT2A | |
| SCHEMBL6742303 | 0.76 | GAA (0.38) | KMT2AMAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6308505 | 0.75 | HPGD (0.49) | KMT2AMAPTHPGDALDH1A1HTT | |
| SCHEMBL28703886 | 0.73 | KIF11 (0.32) | KIF11 | |
| SCHEMBL27386419 | 0.70 | CHRNB2 (0.35) | — | |
| SCHEMBL11097338 | 0.70 | HSD17B10 (0.41) | KMT2AALDH1A1KDM4EAKR1C3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6768024-B1 | CONTROLLING OBESITY, SEXUAL DYSFUNCTION OR INFLAMMATION | LION BIOSCIENCE AG (DE) | 2004-07-27 | — | — | US | disclosed |
| US-4159254-A | FUNGICIDES, BACTERICIDES | MERCK & CO., INC. (US) | 1979-06-26 | — | — | US | disclosed |