Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340647 | 0.86 | TSHR (0.54) | HIF1AALOX15TSHRKDM4ETDP1 | |
| SCHEMBL6474291 | 0.80 | TSHR (0.48) | HIF1AALOX15TSHRKDM4ETDP1 | |
| Orotic Acid SCHEMBL185887 | 0.77 | ALOX15 (0.50) | HIF1AALOX15TSHRKDM4ETDP1 | |
| SCHEMBL2718066 | 0.77 | GAA (0.47) | HIF1AALOX15TSHRTDP1HCAR2 | |
| SCHEMBL31112076 | 0.76 | KDM4E (0.44) | KDM4ETDP1ALDH1A1MAPTLMNA | |
| Acetic Acid SCHEMBL16057478 | 0.76 | GAA (0.38) | TDP1ALDH1A1MAPTLMNASMN1; SMN2 | |
| Acetic Acid SCHEMBL16057481 | 0.76 | GAA (0.38) | TDP1ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL95816 | 0.75 | — | — | |
| SCHEMBL985538 | 0.74 | KMO (0.47) | HIF1AALOX15TSHRKDM4ETDP1 | |
| SCHEMBL8626403 | 0.74 | ALOX15 (0.46) | HIF1AALOX15TSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606606-A | Preparation process of water-based pressure-sensitive adhesive emulsion for paper film | 广州顿尔诺科技有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-120191927-A | Activated carbon multistage adsorption method for matching sizes of background pollutants and micro pollutants | 中国科学院生态环境研究中心 | 2025-06-24 | — | — | CN | disclosed |
| CN-118791436-A | 2-Aminopyrimidine derivative and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-116606606-A | Preparation process of water-based pressure-sensitive adhesive emulsion for paper film | 广州顿尔诺科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116606606-A | Preparation process of water-based pressure-sensitive adhesive emulsion for paper film | 广州顿尔诺科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| EP-2516420-B1 | AMINOALKYLPYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR ANTAGONISTS | MEDICIS PHARMACEUTICAL CORP (US) | 2018-08-22 | — | — | EP | disclosed |
| CN-102803248-B | As the aminoalkyl pyrimidine of histamine H 4 receptor antagonist | MEDICIS PHARMACEUTICAL CORP. (US) | 2015-09-16 | — | — | CN | disclosed |
| US-8901146-B2 | Aminoalkylpyrimidine derivatives as histamine H4 receptor antagonists | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901146-B2 | Aminoalkylpyrimidine derivatives as histamine H4 receptor antagonists | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2014-12-02 | — | — | US | disclosed |
| US-20130018031-A1 | AMINOALKYLPYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR ANTAGONISTS | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2013-01-17 | — | — | US | disclosed |
| US-20130018031-A1 | AMINOALKYLPYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR ANTAGONISTS | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2013-01-17 | — | — | US | disclosed |
| CN-102803248-A | Aminoalkylpyrimidine derivatives as histamine H4 receptor antagonists | PALAU PHARMA SA | 2012-11-28 | — | — | CN | disclosed |
| WO-2011076878-A1 | AMINOALKYLPYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR ANTAGONISTS | PALAU PHARMA, S.A. (ES) | 2011-06-30 | — | — | WO | disclosed |
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |
| US-4689328-A | CARBOXY-PYRIMIDINE DERIVATIVES | RESEARCH CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018031-A1 | AMINOALKYLPYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR ANTAGONISTS | HRH4, HRH2, HRH3 | HIF1A 2615/4885ALOX15 2798/4885TSHR 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.