Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705265 | 0.87 | ALOX15 (0.56) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| Orotic Acid SCHEMBL9443769 | 0.85 | KDM4E (0.46) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| Orotic Acid SCHEMBL28231800 | 0.81 | ALOX15 (0.35) | ALOX15TSHRHIF1A | |
| SCHEMBL11013946 | 0.81 | ALOX15 (0.30) | ALOX15TSHRHIF1A | |
| SCHEMBL12086579 | 0.79 | LMNA (0.31) | LMNA | |
| SCHEMBL10479187 | 0.79 | ALOX15 (0.48) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL3455658 | 0.79 | LMNA (0.50) | TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL14537021 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6301920 | 0.77 | HIF1A (0.46) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL8626403 | 0.77 | ALOX15 (0.46) | ALOX15TSHRHIF1AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138879-A1 | MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH | KISUMA CHEMICALS B V (NL) | 2026-05-21 | — | — | US | claimed |
| EP-4605346-A1 | MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH | Kisuma Chemicals B.V. (NL) | 2025-08-27 | — | — | EP | claimed |
| WO-2024085755-A1 | MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH | KISUMA CHEMICALS B.V. (NL) | 2024-04-25 | — | — | WO | claimed |
| CN-109761916-A | A kind of improvement synthetic method of orotic acid | 成都百事兴科技实业有限公司 | 2019-05-17 | — | — | CN | claimed |
| EP-3084042-B1 | DEPOSITION OF COPPER-TIN AND COPPER-TIN-ZINC ALLOYS FROM AN ELECTROLYTE | UMICORE GALVANOTECHNIK GMBH (DE) | 2018-11-07 | — | — | EP | claimed |
| US-20160348259-A1 | DEPOSITION OF COPPER-TIN AND COPPER-TIN-ZINC ALLOYS FROM AN ELECTROLYTE | UMICORE GALVANOTECHNIK GMBH (DE) | 2016-12-01 | — | — | US | claimed |
| CN-101467968-A | Preparation for novel administration route of antiarrhythmic medicament | ZHEJIANG ZHENGFANG PHARMACEUTI (CN) | 2009-07-01 | — | — | CN | claimed |
| US-20260138879-A1 | MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH | KISUMA CHEMICALS B V (NL) | 2026-05-21 | — | — | US | disclosed |
| EP-4605346-A1 | MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH | Kisuma Chemicals B.V. (NL) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024085755-A1 | MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH | KISUMA CHEMICALS B.V. (NL) | 2024-04-25 | — | — | WO | disclosed |
| CN-112779303-B | Method for synthesizing orotic acid by biological enzyme method | 华东理工大学 | 2023-05-02 | — | — | CN | disclosed |
| US-20230096028-A1 | BICYCLIC HETEROCYCLYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. | 2023-03-30 | — | — | US | disclosed |
| EP-3930845-A1 | BICYCLIC HETEROCYCLYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |
| WO-1992020816-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1992-11-26 | — | — | WO | disclosed |
| US-4873228-A | 2-oxo-4-carboxy-pyrimidines and their use as anti-malaria and anti-cancer agents | THE UNIVERSITY OF MELBOURNE (AU) | 1989-10-10 | — | — | US | disclosed |
| EP-0260057-A2 | 2-Oxo-4-carboxy-pyrimidines | THE UNIVERSITY OF MELBOURNE (AU) | 1988-03-16 | — | — | EP | disclosed |
| US-4689328-A | CARBOXY-PYRIMIDINE DERIVATIVES | RESEARCH CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |
| US-4508723-A | 6-Azaoligocycloalkylmethyleneaminopenam compounds | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| US-4495201-A | Pharmaceutical composition and method for treating heart diseases therewith | INSTITUT ORGANICHESKOI KHIMII IMENI N.D. ZELINSKOGO (SU) | 1985-01-22 | — | — | US | disclosed |
| US-4430495-A | Process for preparing lincomycin and clindamycin ribonucleotides | THE UPJOHN COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230096028-A1 | BICYCLIC HETEROCYCLYL COMPOUNDS AND USES THEREOF | SOST, SOS1, IQGAP1 | ALOX15 2579/4885TSHR 4035/4885HIF1A 1142/4885 |
| US-20260138879-A1 | MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH | LDHA, LDHB, ME2 | ALOX15 959/4885TSHR 4832/4885HIF1A 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.