Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651832 | 0.82 | ALOX15 (0.50) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| Orotic Acid SCHEMBL185887 | 0.77 | ALOX15 (0.50) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL4288196 | 0.77 | SMN1; SMN2 (0.46) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL97719 | 0.75 | — | — | |
| SCHEMBL6301920 | 0.74 | HIF1A (0.46) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL985538 | 0.74 | KMO (0.47) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL8207621 | 0.73 | MEN1 (0.30) | ALDH1A1 | |
| SCHEMBL11381523 | 0.73 | ALOX15 (0.50) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| Water SCHEMBL9423366 | 0.72 | KMO (0.46) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL29199087 | 0.72 | ALOX15 (0.61) | ALOX15TSHRHIF1AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| EP-0050261-B1 | MOULDING MASSES STABILIZED AGAINST THERMOLYSIS WITH A LOW MONOMER CONTENT | BAYER AG (DE) | 1985-08-14 | — | — | EP | disclosed |
| EP-0050261-A1 | Moulding masses stabilized against thermolysis with a low monomer content | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |