Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494390 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL18319260 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL1187473 | 0.74 | ALDH1A1 (0.65) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL7401545 | 0.72 | ALDH1A1 (0.69) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL1494350 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL3375102 | 0.72 | KDM4E (0.57) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL29933323 | 0.72 | KDM4E (0.57) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL629627 | 0.72 | NPC1 (0.60) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL17632769 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL630196 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRTDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419409-A1 | PROCESS FOR THE PREPARATION OF A BIPHENYL-2-YLCARBAMIC ACID ESTER | Glaxo Group Limited (GB) | 2012-02-22 | — | — | EP | disclosed |