Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455897 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL1187473 | 0.73 | ALDH1A1 (0.65) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL30163502 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL7401545 | 0.71 | ALDH1A1 (0.69) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL629627 | 0.71 | NPC1 (0.60) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL29933323 | 0.71 | KDM4E (0.57) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL3375102 | 0.71 | KDM4E (0.57) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL630195 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL17632769 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL16750374 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KDM4ETDP1ERN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419409-A1 | PROCESS FOR THE PREPARATION OF A BIPHENYL-2-YLCARBAMIC ACID ESTER | Glaxo Group Limited (GB) | 2012-02-22 | — | — | EP | disclosed |