Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310000 | 0.94 | HDAC3 (0.32) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6302634 | 0.91 | PARP1 (0.33) | — | |
| SCHEMBL6302932 | 0.86 | PARP1 (0.34) | — | |
| SCHEMBL6302740 | 0.83 | HDAC3 (0.43) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7979345 | 0.82 | GAA (0.34) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6303033 | 0.80 | L3MBTL1 (0.37) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6304845 | 0.79 | PARP1 (0.39) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6310829 | 0.79 | RIPK1 (0.36) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6309334 | 0.79 | HDAC3 (0.31) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6302989 | 0.78 | HDAC3 (0.35) | HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841550-B1 | Benzoxazine and benzothiazine derivatives and their use in medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | disclosed |