Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302740 | 0.86 | HDAC3 (0.43) | GAAALDH1A1TSHRHDAC3HDAC1 | |
| SCHEMBL7978190 | 0.85 | GAA (0.33) | GAAALDH1A1LMNATSHRHDAC3 | |
| SCHEMBL6303033 | 0.84 | L3MBTL1 (0.37) | GAAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6310829 | 0.84 | RIPK1 (0.36) | TSHRHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6302989 | 0.83 | HDAC3 (0.35) | TSHRHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6608622 | 0.83 | GAA (0.32) | GAAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5189245 | 0.83 | SSTR4 (0.32) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5188660 | 0.83 | SSTR4 (0.32) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6303012 | 0.82 | HDAC3 (0.31) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6302903 | 0.81 | NR1D1 (0.37) | ALDH1A1LMNAHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081324-A1 | BENZOXAZINE DERIVATIVES AND BENZOTHIAZINE DERIVATIVES HAVING NOS-INHIBITORY AND ANTIOXIDANT PROPERTIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-01 | — | — | WO | disclosed |