Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.63 |
| ▸ | JUN | P05412 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362833 | 1.00 | MAPT (0.65) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL63054 | 1.00 | MAPT (0.65) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL10438847 | 0.88 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL69522 | 0.88 | ALDH1A1 (0.58) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL11061667 | 0.86 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL2933196 | 0.86 | IAPP (0.67) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL2933198 | 0.86 | IAPP (0.67) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL28343398 | 0.85 | NFKB1 (0.68) | MAPTKDM4ELMNANFKB1NFE2L2 | |
| SCHEMBL30673968 | 0.85 | NFKB1 (0.68) | MAPTKDM4ELMNANFKB1NFE2L2 | |
| SCHEMBL7108533 | 0.84 | MAPT (0.55) | MAPTALDH1A1KDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109401605-A | Thermosetting composition, cured film and colored filter | 捷恩智株式会社 | 2019-03-01 | — | — | CN | claimed |
| US-3998851-A | PREPARATION OF COUMARINS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-12-21 | — | — | US | claimed |
| US-20250188023-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-06-12 | — | — | US | disclosed |
| EP-4545512-A1 | NOVEL CINNAMAMIDE DERIVATIVE AND USE THEREOF | Korea Research Institute of Bioscience and Biotechnology (KR) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731151-A | Novel cinnamide derivative and use thereof | 韩国生命工学研究院 | 2025-03-28 | — | — | CN | disclosed |
| US-12258308-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-03-25 | — | — | US | disclosed |
| US-20250082620-A1 | NOVEL CINNAMAMIDE DERIVATIVES AND USE THEREOF | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2025-03-13 | — | — | US | disclosed |
| WO-2023249288-A1 | NOVEL CINNAMAMIDE DERIVATIVE AND USE THEREOF | 한국생명공학연구원 | 2023-12-28 | — | — | WO | disclosed |
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| US-20220089532-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-24 | — | — | US | disclosed |
| US-11261154-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-01 | — | — | US | disclosed |
| US-4906661-A | Esters of aryloxypropanolamine derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4804677-A | CARDIOTONIC AGENTS; GLAUCOMA; SIDE-EFFECT REDUCTION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| US-4692446-A | ADRENERGIC BLOCKING AGENTS | E. I. DU PONT DE NEMOURS & CO., INC. (US) | 1987-09-08 | — | — | US | disclosed |
| US-4623652-A | ADRENERGIC BLOCKING AGENTS | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0093155-B1 | ESTERS OF ARYLOXYPROPANOLAMINE DERIVATIVES AND USE AS BETA-ADRENERGIC BLOCKING AGENTS | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0093155-A4 | ESTERS OF ARYLOXYPROPANOLAMINE DERIVATIVES AND USE AS BETA-ADRENERGIC BLOCKING AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-04-24 | — | — | EP | disclosed |
| EP-0093155-A1 | ESTERS OF ARYLOXYPROPANOLAMINE DERIVATIVES AND USE AS BETA-ADRENERGIC BLOCKING AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-11-09 | — | — | EP | disclosed |
| WO-1983001772-A1 | ESTERS OF ARYLOXYPROPANOLAMINE DERIVATIVES AND USE AS 'beta'-ADRENERGIC BLOCKING AGENTS | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-05-26 | — | — | WO | disclosed |
| US-3998851-A | PREPARATION OF COUMARINS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250082620-A1 | NOVEL CINNAMAMIDE DERIVATIVES AND USE THEREOF | CCAR2, ATF4, CREBBP | MAPT 4323/4885ALDH1A1 110/4885KDM4E 2304/4885 |
| US-12258308-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | MAPT 2169/4885ALDH1A1 1189/4885KDM4E 2022/4885 |
| US-11261154-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | MAPT 2169/4885ALDH1A1 1189/4885KDM4E 2022/4885 |
| US-20250188023-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | MAPT 2085/4885ALDH1A1 1203/4885KDM4E 1914/4885 |
| US-20220089532-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | MAPT 2169/4885ALDH1A1 1189/4885KDM4E 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.