Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | RBP4 | P02753 | 5/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630911 | 0.90 | RBP4 (0.35) | SLC6A9RBP4LMNASMN1; SMN2TSHR | |
| SCHEMBL631571 | 0.89 | RBP4 (0.48) | RBP4ALDH1A1SMN1; SMN2MAPTHSD11B1 | |
| SCHEMBL630684 | 0.88 | RBP4 (0.34) | RBP4MAPT | |
| SCHEMBL631287 | 0.87 | RBP4 (0.34) | RBP4LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL631926 | 0.87 | RBP4 (0.34) | RBP4MAPT | |
| SCHEMBL766175 | 0.75 | RBP4 (0.47) | SLC6A9RBP4NOTUMLMNAKDM4E | |
| SCHEMBL631983 | 0.68 | RBP4 (0.46) | RBP4 | |
| SCHEMBL630486 | 0.66 | RBP4 (0.55) | RBP4LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL766166 | 0.65 | RBP4 (0.74) | RBP4LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL630561 | 0.65 | PKM (0.53) | RBP4LMNAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |