Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630911 | 0.90 | RBP4 (0.35) | RBP4BRD4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL630560 | 0.89 | SLC6A9 (0.36) | RBP4HSD11B1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL630684 | 0.88 | RBP4 (0.34) | RBP4MAPT | |
| SCHEMBL631287 | 0.87 | RBP4 (0.34) | RBP4MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL631926 | 0.87 | RBP4 (0.34) | RBP4MAPT | |
| SCHEMBL766203 | 0.75 | RBP4 (0.56) | RBP4BRD4PTGDR2CETPOPRK1 | |
| SCHEMBL631983 | 0.68 | RBP4 (0.46) | RBP4RAB9A | |
| SCHEMBL630574 | 0.66 | RBP4 (0.73) | RBP4MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL632040 | 0.65 | RBP4 (1.00) | RBP4PTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL30996959 | 0.65 | RBP4 (1.00) | RBP4PTGDR2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |