Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630911 | 0.88 | RBP4 (0.35) | RBP4MAPT | |
| SCHEMBL630560 | 0.87 | SLC6A9 (0.36) | RBP4MAPT | |
| SCHEMBL631571 | 0.87 | RBP4 (0.48) | RBP4MAPT | |
| SCHEMBL630684 | 0.86 | RBP4 (0.34) | RBP4MAPT | |
| SCHEMBL631287 | 0.85 | RBP4 (0.34) | RBP4MAPT | |
| SCHEMBL766213 | 0.76 | RBP4 (0.40) | RBP4MAPTXIAPBIRC2 | |
| SCHEMBL3722493 | 0.67 | CRHR1 (0.31) | RBP4 | |
| SCHEMBL630667 | 0.66 | PKM (0.54) | RBP4MAPT | |
| SCHEMBL631983 | 0.66 | RBP4 (0.46) | RBP4 | |
| SCHEMBL766189 | 0.66 | RBP4 (0.63) | RBP4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |