Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 8/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630680 | 0.92 | KCNQ1 (0.48) | POLBBDKRB1KCNQ1MMP1KMT2A | |
| SCHEMBL631181 | 0.90 | LMNA (0.44) | POLBBDKRB1KCNQ1MMP1CHRM2 | |
| SCHEMBL8269061 | 0.90 | POLB (0.53) | POLBBDKRB1KCNQ1USP30HCRTR1 | |
| SCHEMBL630004 | 0.90 | POLB (0.53) | POLBBDKRB1KCNQ1USP30HCRTR1 | |
| SCHEMBL13206972 | 0.90 | POLB (0.53) | POLBBDKRB1KCNQ1USP30HCRTR1 | |
| SCHEMBL631414 | 0.89 | POLB (0.42) | POLBBDKRB1KCNQ1MEN1KMT2A | |
| SCHEMBL630231 | 0.82 | EPHX2 (0.44) | POLBBDKRB1MEN1KMT2AL3MBTL1 | |
| SCHEMBL630671 | 0.82 | POLB (0.46) | POLBBDKRB1KCNQ1MMP1CHRM2 | |
| SCHEMBL1383477 | 0.82 | KCNQ1 (0.56) | POLBKCNQ1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL629759 | 0.82 | KCNQ1 (0.56) | POLBKCNQ1KMT2AHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |