Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307392 | 1.00 | MAPT (0.50) | MAPTTHRBRECQLKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6310605 | 0.98 | MAPT (0.53) | MAPTTHRBRECQLKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6310602 | 0.98 | MAPT (0.53) | MAPTTHRBRECQLKMT2ATDP1 | |
| SCHEMBL27352743 | 0.77 | PDE10A (0.48) | MAPTTHRBKMT2AMEN1CASP1 | |
| SCHEMBL14064972 | 0.77 | PDE10A (0.48) | MAPTTHRBKMT2AMEN1CASP1 | |
| SCHEMBL6311663 | 0.76 | ALDH1A1 (0.38) | MAPTTHRBRECQLKMT2ATDP1 | |
| SCHEMBL6311659 | 0.76 | ALDH1A1 (0.38) | MAPTTHRBRECQLKMT2ATDP1 | |
| SCHEMBL22890834 | 0.76 | THRB (0.52) | MAPTTHRBRECQLKMT2ATDP1 | |
| SCHEMBL1682394 | 0.76 | KMT2A (0.63) | MAPTTHRBRECQLKMT2ATDP1 | |
| SCHEMBL31268209 | 0.76 | KMT2A (0.63) | MAPTTHRBRECQLKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849766-B2 | 1,4-diamino-2-alkenylbenzene derivatives, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | claimed |
| EP-1351921-B1 | NOVEL 1,4-DIAMINO-2-ALKENYL-BENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-12-01 | — | — | EP | claimed |
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-03 | — | — | US | claimed |
| US-6849766-B2 | 1,4-diamino-2-alkenylbenzene derivatives, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| EP-1351921-B1 | NOVEL 1,4-DIAMINO-2-ALKENYL-BENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | AOC1, AOX1, GPX1 | MAPT 818/4885THRB 3258/4885RECQL 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.