Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508441 | 0.91 | MEN1 (0.46) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6310041 | 0.84 | LMNA (0.38) | KMT2AMAPTALDH1A1LMNANPC1 | |
| SCHEMBL3075097 | 0.84 | MEN1 (0.40) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3066645 | 0.83 | KCNA5 (0.43) | NPSR1MAPTKCNA5 | |
| SCHEMBL6309522 | 0.80 | MAPT (0.38) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6511048 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL3069248 | 0.75 | CNR2 (0.37) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6308945 | 0.75 | LMNA (0.40) | KMT2AALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3076912 | 0.73 | FFAR1 (0.43) | KMT2AALDH1A1LMNAKCNA5 | |
| SCHEMBL3069083 | 0.73 | KCNA5 (0.44) | MAPTALDH1A1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | NPSR1 3272/4885MEN1 1608/4885KMT2A 1213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.