Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310041 | 0.80 | LMNA (0.38) | ALDH1A1POLBKMT2AMAPTTSHR | |
| SCHEMBL6505850 | 0.80 | CTSA (0.41) | ALDH1A1SMN1; SMN2TSHRTBXAS1GRM8 | |
| SCHEMBL6308396 | 0.78 | NPSR1 (0.47) | ALDH1A1KMT2AMAPTHPGDMEN1 | |
| SCHEMBL5160712 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KMT2ATBXAS1PKM | |
| SCHEMBL5929551 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KMT2ATBXAS1PKM | |
| SCHEMBL3066645 | 0.75 | KCNA5 (0.43) | MAPT | |
| SCHEMBL7421414 | 0.72 | KMT2A (0.57) | ALDH1A1POLBSMN1; SMN2KMT2AMAPT | |
| SCHEMBL9159608 | 0.72 | CYP2C19 (0.46) | ALDH1A1SMN1; SMN2HPGDTBXAS1CFTR | |
| SCHEMBL6505819 | 0.70 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2TBXAS1CFTRSLC6A2 | |
| SCHEMBL9592454 | 0.69 | SMN1; SMN2 (0.70) | SMN1; SMN2TSHRTBXAS1CFTRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |