Oxaloacetate

Oxaloacetate

SCHEMBL6310306

C.O=C(O)CC(=O)C(=O)O.O=C(O)CC(=O)C(=O)O.O=C(O)CC(=O)C(=O)O.O=C(O)CC(=O)C(=O)O

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LDHA P00338 1/20 0.53
▸ SRR Q9GZT4 1/20 0.53
▸ OR51E2 Q9H255 3/20 0.47
▸ EGLN1 Q9GZT9 2/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ SLC13A3 Q8WWT9 1/20 0.47
▸ FEN1 P39748 6/20 0.40
▸ ERCC5 P28715 5/20 0.40
▸ PTPN1 P18031 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ HAO1 Q9UJM8 3/20 0.37
▸ ALOX15 P16050 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ LMNA P02545 1/20 0.35
▸ ALKBH5 Q6P6C2 1/20 0.35
▸ SUCNR1 Q9BXA5 1/20 0.35
▸ FFAR3 O14843 1/20 0.33
▸ GLRA1 P23415 1/20 0.33
▸ SLC6A9 P48067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxaloacetate SCHEMBL20912993 1.00 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL4298763 0.96 LDHA (0.57) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL8464 0.96 — —
Oxaloacetate SCHEMBL898612 0.96 LDHA (0.57) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL25210523 0.93 — —
Oxaloacetate SCHEMBL11328361 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9782818 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL8638879 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL9994505 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1
Oxaloacetate SCHEMBL6545252 0.93 LDHA (0.53) LDHASRROR51E2EGLN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102340-A1 GENETICALLY ENGINEERED YEAST STRAINS PRODUCING MALIC ACID ARCHER-DANIELS-MIDLAND COMPANY (US) 2026-05-15 — — WO disclosed
US-12522808-B2 Modified polypeptide with attenuated activity of citrate synthase and method for producing L-amino acid using the same CJ Chieljedang Corporation (KR) 2026-01-13 — — US disclosed
US-20250290078-A1 HMO PRODUCING MICROORGANISM WITH INCREASED ROBUSTNESS TOWARDS GLUCOSE GRADIENTS DSM IP ASSETS B.V. (NL) 2025-09-18 — — US disclosed
EP-4514989-A1 HMO PRODUCING MICROORGANISM WITH INCREASED ROBUSTNESS TOWARDS GLUCOSE GRADIENTS DSM IP Assets B.V. (NL) 2025-03-05 — — EP disclosed
CN-119095975-A HMO-producing microorganism with improved robustness to glucose gradients 帝斯曼知识产权资产管理有限公司 2024-12-06 — — CN disclosed
US-20240182872-A1 NOVEL CITRATE SYNTHASE VARIANT AND METHOD FOR PRODUCING L-AMINO ACIDS USING SAME CJ CHEILJEDANG CORPORATION (KR) 2024-06-06 — — US disclosed
CN-115175993-B Novel modified polypeptide having reduced citrate synthase activity and method for producing L-amino acid using the same CJ第一制糖株式会社 2024-06-04 — — CN disclosed
US-20240150731-A1 NOVEL CITRATE SYNTHASE VARIANT AND METHOD FOR PRODUCING L-VALINE USING THE SAME CJ CHEILJEDANG CORPORATION (KR) 2024-05-09 — — US disclosed
US-20240150730-A1 NOVEL CITRATE SYNTHASE VARIANT AND METHOD FOR PRODUCING O-ACETYL-L-HOMOSERINE OR L-METHIONINE USING SAME CJ CHEILJEDANG CORPORATION (KR) 2024-05-09 — — US disclosed
CN-112175895-B Modified polypeptides having reduced citrate synthase activity and methods of producing L-amino acids using the same CJ第一制糖株式会社 2024-05-03 — — CN disclosed
EP-3959229-A1 GENE TARGETS FOR NITROGEN FIXATION TARGETING FOR IMPROVING PLANT TRAITS Pivot Bio, Inc. (US) 2022-03-02 — — EP disclosed
EP-3945789-A1 LOW-METHANE RICE Sun, Chuanxin (SE) 2022-02-09 — — EP disclosed
US-6919190-B2 Regulation of carbon assimilation ARCHER-DANIELS-MIDLAND COMPANY (US) 2005-07-19 — — US disclosed
EP-1032403-A4 NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES BLASS JOHN P (US) 2004-03-31 — — EP disclosed
US-6599732-B1 Nucleotide sequences coding phosphoenolpyruvate carboxylase for use in process carbon dioxide ARCHER-DANIELS-MIDLAND COMPANY 2003-07-29 — — US disclosed
US-20020151010-A1 Regulation of carbon assimilation ARCHER-DANIELS-MIDLAND COMPANY 2002-10-17 — — US disclosed
EP-1196611-A1 REGULATION OF CARBON ASSIMILATION Archer-Daniels-Midland Company (US) 2002-04-17 — — EP disclosed
WO-2001000852-A1 REGULATION OF CARBON ASSIMILATION ARCHER-DANIELS-MIDLAND COMPANY (US) 2001-01-04 — — WO disclosed
EP-1032403-A1 NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES CORNELL RESEARCH FOUNDATION, INC. (US) 2000-09-06 — — EP disclosed
WO-1999021565-A1 NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES CORNELL RESEARCH FOUNDATION, INC. (US) 1999-05-06 — — WO disclosed
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