Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4A | O75164 | 2/20 | 0.58 |
| ▸ | KDM4B | O94953 | 2/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603304 | 0.88 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4AKDM4B | |
| SCHEMBL419446 | 0.87 | MAPT (0.65) | NPC1RAB9ASMN1; SMN2KDM4AKDM4B | |
| SCHEMBL3180253 | 0.81 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4AKDM4B | |
| SCHEMBL8881445 | 0.81 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4AKDM4B | |
| SCHEMBL21066336 | 0.80 | L3MBTL1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL419064 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27827106 | 0.80 | AMY1A (0.63) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL28251184 | 0.79 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2KDM4AKDM4B | |
| SCHEMBL5717620 | 0.78 | KDM4E (0.74) | NPC1RAB9ASMN1; SMN2KDM4AKDM4B | |
| SCHEMBL3260627 | 0.78 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4AKDM4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | MITSUI CHEMICALS, INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1489073-A1 | PROCESS FORPREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES | MITSUI CHEMICALS, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | CBR3, CBR1, IDH1 | NPC1 3375/4885RAB9A 2103/4885SMN1; SMN2 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.