Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312958 | 0.85 | ITGB2 (0.41) | KDM4EALDH1A1MAPTCA1CA2 | |
| SCHEMBL6310553 | 0.74 | ITGAL (0.49) | KDM4EKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6312245 | 0.72 | ITGB2 (0.42) | KDM4EKMT2ATTRAPPALDH1A1 | |
| SCHEMBL6198213 | 0.71 | PRKDC (0.45) | KDM4EKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6312233 | 0.69 | HPGD (0.53) | KDM4EKMT2AAPPALDH1A1HPGD | |
| SCHEMBL6567144 | 0.67 | ITGB2 (0.49) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL23690433 | 0.67 | L3MBTL1 (0.55) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL6316872 | 0.67 | ITGB2 (0.38) | KMT2AALDH1A1MAPTHPGDSTAT3 | |
| SCHEMBL29366984 | 0.66 | HSD11B1 (0.65) | KDM4EKMT2ASMN1; SMN2TTRAPP | |
| SCHEMBL2152935 | 0.66 | HSD11B1 (0.65) | KDM4EKMT2ASMN1; SMN2TTRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |