Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317979 | 0.87 | ADORA3 (0.43) | ENPP2ALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL6311004 | 0.86 | ENPP2 (0.43) | ENPP2ALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL6312701 | 0.85 | ENPP2 (0.43) | ENPP2ALDH1A1ARKDM4ESMN1; SMN2 | |
| SCHEMBL6319758 | 0.83 | ENPP2 (0.41) | ENPP2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL6310705 | 0.82 | ENPP2 (0.39) | ENPP2ALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL6318124 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RXFP1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL6310328 | 0.79 | NPSR1 (0.44) | ENPP2ALDH1A1RXFP1KDM4ESMN1; SMN2 | |
| SCHEMBL6318776 | 0.79 | ALDH1A1 (0.41) | ENPP2ALDH1A1RXFP1SMN1; SMN2LMNA | |
| SCHEMBL6311410 | 0.79 | PIK3CD (0.38) | ENPP2ALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL6311689 | 0.79 | ALDH1A1 (0.40) | ALDH1A1RXFP1KDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | ENPP2 4010/4885ALDH1A1 2550/4885RXFP1 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.