Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309853 | 0.90 | ALDH1A1 (0.41) | ALDH1A1RXFP1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL6310367 | 0.76 | HTT (0.43) | ALDH1A1RXFP1SMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL6311550 | 0.75 | KDM4E (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4ENPSR1 | |
| SCHEMBL6311104 | 0.73 | ENPP2 (0.41) | ALDH1A1RXFP1SMN1; SMN2MAPTHPGD | |
| SCHEMBL6318124 | 0.72 | ALDH1A1 (0.43) | ALDH1A1RXFP1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL6311689 | 0.72 | ALDH1A1 (0.40) | ALDH1A1RXFP1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL6311597 | 0.70 | NPSR1 (0.52) | ALDH1A1RXFP1SMN1; SMN2MAPTHPGD | |
| SCHEMBL6311836 | 0.70 | GRM2 (0.41) | ALDH1A1SMN1; SMN2MAPTL3MBTL1HPGD | |
| SCHEMBL6310328 | 0.69 | NPSR1 (0.44) | ALDH1A1RXFP1SMN1; SMN2MAPTHPGD | |
| SCHEMBL6311004 | 0.69 | ENPP2 (0.43) | ALDH1A1SMN1; SMN2CYP2C9MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | ALDH1A1 2550/4885RXFP1 1521/4885SMN1; SMN2 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.