Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.82 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.82 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.82 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.82 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KDM5C | P41229 | 3/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM6B | O15054 | 2/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL24441 | 0.95 | — | — | |
| Succinic Acid SCHEMBL11729884 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL27309703 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL156758 | 0.95 | — | — | |
| Succinic Acid SCHEMBL8141952 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL3204318 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL27505704 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL2222412 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL9639568 | 0.91 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL10907381 | 0.91 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9622951-B2 | Personal care compositions | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-18 | — | — | US | claimed |
| CN-104768523-A | Personal care compositions having a tan delta of 0.30 or more at 10 DEG C | PROCTER & GAMBLE | 2015-07-08 | — | — | CN | claimed |
| WO-2014070689-A1 | PERSONAL CARE COMPOSITIONS HAVING A TAN DELTA OF 0.30 OR MORE AT 10°C | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-08 | — | — | WO | claimed |
| US-20140121268-A1 | Personal Care Compositions | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-01 | — | — | US | claimed |
| US-12576019-B2 | Personal cleansing composition with an organic acid having a pKa greater than 2.7 | THE PROCTER & GAMBLE COMPANY (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4362903-B1 | CLEANSING COMPOSITION WITH PYRROLIDONE CARBOXYLIC ACID | PROCTER & GAMBLE (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20260027132-A1 | FRAGRANCE COMPOSITIONS AND USE THEREOF FOR IMPROVING SLEEP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2026-01-29 | — | — | US | disclosed |
| US-12453736-B2 | Fragrance compositions and use thereof for improving sleep | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2025-10-28 | — | — | US | disclosed |
| EP-4255375-B1 | HAIR CARE COMPOSITION COMPRISING MALODOR REDUCTION MATERIALS | PROCTER & GAMBLE (US) | 2025-08-13 | — | — | EP | disclosed |
| US-12357551-B2 | Antibacterial cleansing composition, uses and methods | THE PROCTER & GAMBLE COMPANY (US) | 2025-07-15 | — | — | US | disclosed |
| CN-119156199-A | Antibacterial cleaning composition, use and method | 宝洁公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-119033604-A | Hair care composition comprising malodor reduction composition | 宝洁公司 | 2024-11-29 | — | — | CN | disclosed |
| EP-2032683-A1 | CLEANSING BAR COMPOSITIONS COMPRISING A HIGH LEVEL OF WATER | The Procter and Gamble Company (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008070015-A1 | CLEANSING BAR COMPOSITIONS COMPRISING A HIGH LEVEL OF WATER | THE PROCTER & GAMBLE COMPANY (US) | 2008-06-12 | — | — | WO | disclosed |
| CN-101198687-A | Cleansing bar compositions comprising high water content | PROCTER & GAMBLE (US) | 2008-06-11 | — | — | CN | disclosed |
| WO-2008065629-A1 | PACKAGING FOR HIGH MOISTURE BAR SOAP | THE PROCTER & GAMBLE COMPANY (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080020959-A1 | Cleansing bar compositions comprising a high level of water | THE PROCTER & GAMBLE COMPANY | 2008-01-24 | — | — | US | disclosed |
| WO-2007146027-A1 | CLEANSING BAR COMPOSITIONS COMPRISING A HIGH LEVEL OF WATER | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070155639-A1 | Cleansing bar compositions comprising a high level of water | PROCTER & GAMBLE COMPANY, THE | 2007-07-05 | — | — | US | disclosed |
| US-20070021314-A1 | Cleansing bar compositions comprising a high level of water | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027132-A1 | FRAGRANCE COMPOSITIONS AND USE THEREOF FOR IMPROVING SLEEP | B2M, PER2, CHRM2 | LMNA 761/4885EGLN1 906/4885ALKBH5 137/4885 |
| US-12576019-B2 | Personal cleansing composition with an organic acid having a pKa greater than 2.7 | CUTA, SPHK2, SPHK1 | LMNA 566/4885EGLN1 347/4885ALKBH5 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.