Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.55 |
| ▸ | FES | P07332 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.55 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.55 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.55 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312465 | 0.86 | SMN1; SMN2 (0.57) | NPC1SMN1; SMN2RAB9AKMT2AALDH1A1 | |
| SCHEMBL16078325 | 0.78 | MEN1 (0.62) | NPC1SMN1; SMN2RAB9AKMT2ATP53 | |
| SCHEMBL17107205 | 0.78 | NPC1 (0.57) | NPC1SMN1; SMN2RAB9AKMT2ATP53 | |
| SCHEMBL2766185 | 0.78 | HPGD (0.64) | SMN1; SMN2RAB9AKMT2ATP53ALDH1A1 | |
| SCHEMBL11996511 | 0.77 | NPC1 (0.56) | NPC1SMN1; SMN2RAB9AKMT2ATP53 | |
| SCHEMBL24770658 | 0.76 | MAPK1 (0.62) | NPC1SMN1; SMN2RAB9AKMT2ATP53 | |
| SCHEMBL354761 | 0.75 | APLNR (0.50) | NPC1SMN1; SMN2RAB9AKMT2ATP53 | |
| SCHEMBL30058880 | 0.75 | ALDH1A1 (0.53) | NPC1SMN1; SMN2RAB9AKMT2ATP53 | |
| SCHEMBL16073069 | 0.75 | RAB9A (0.72) | NPC1SMN1; SMN2RAB9AKMT2ATP53 | |
| SCHEMBL6311709 | 0.74 | TP53 (0.78) | NPC1SMN1; SMN2RAB9AKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | MITSUI CHEMICALS, INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1489073-A1 | PROCESS FORPREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES | MITSUI CHEMICALS, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | CBR3, CBR1, IDH1 | NPC1 3375/4885SMN1; SMN2 4217/4885RAB9A 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.