Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.59 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL24440 | 0.96 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL3012461 | 0.96 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL30712481 | 0.96 | FFAR3 (0.56) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL156757 | 0.96 | — | — | |
| Succinic Acid SCHEMBL351829 | 0.92 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL8441137 | 0.92 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL7759484 | 0.92 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL2923816 | 0.92 | FFAR3 (0.59) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL9768438 | 0.92 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Succinic Acid SCHEMBL3862916 | 0.92 | FFAR3 (0.53) | HDAC3HDAC1HDAC2HDAC8FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9622951-B2 | Personal care compositions | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-18 | — | — | US | claimed |
| WO-2014070689-A1 | PERSONAL CARE COMPOSITIONS HAVING A TAN DELTA OF 0.30 OR MORE AT 10°C | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-08 | — | — | WO | claimed |
| US-20140121268-A1 | Personal Care Compositions | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-01 | — | — | US | claimed |
| US-12576019-B2 | Personal cleansing composition with an organic acid having a pKa greater than 2.7 | THE PROCTER & GAMBLE COMPANY (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4362903-B1 | CLEANSING COMPOSITION WITH PYRROLIDONE CARBOXYLIC ACID | PROCTER & GAMBLE (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20260027132-A1 | FRAGRANCE COMPOSITIONS AND USE THEREOF FOR IMPROVING SLEEP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2026-01-29 | — | — | US | disclosed |
| US-12453736-B2 | Fragrance compositions and use thereof for improving sleep | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2025-10-28 | — | — | US | disclosed |
| EP-4255375-B1 | HAIR CARE COMPOSITION COMPRISING MALODOR REDUCTION MATERIALS | PROCTER & GAMBLE (US) | 2025-08-13 | — | — | EP | disclosed |
| US-12357551-B2 | Antibacterial cleansing composition, uses and methods | THE PROCTER & GAMBLE COMPANY (US) | 2025-07-15 | — | — | US | disclosed |
| CN-119156199-A | Antibacterial cleaning composition, use and method | 宝洁公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-119033604-A | Hair care composition comprising malodor reduction composition | 宝洁公司 | 2024-11-29 | — | — | CN | disclosed |
| EP-2084083-A1 | PACKAGING FOR HIGH MOISTURE BAR SOAP | The Procter & Gamble Company (US) | 2009-08-05 | — | — | EP | disclosed |
| US-20090143267-A1 | Packaging for high moisture bar soap | THE PROCTER & GAMBLE COMPANY | 2009-06-04 | — | — | US | disclosed |
| EP-2032683-A1 | CLEANSING BAR COMPOSITIONS COMPRISING A HIGH LEVEL OF WATER | The Procter and Gamble Company (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008070015-A1 | CLEANSING BAR COMPOSITIONS COMPRISING A HIGH LEVEL OF WATER | THE PROCTER & GAMBLE COMPANY (US) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008065629-A1 | PACKAGING FOR HIGH MOISTURE BAR SOAP | THE PROCTER & GAMBLE COMPANY (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080020959-A1 | Cleansing bar compositions comprising a high level of water | THE PROCTER & GAMBLE COMPANY | 2008-01-24 | — | — | US | disclosed |
| WO-2007146027-A1 | CLEANSING BAR COMPOSITIONS COMPRISING A HIGH LEVEL OF WATER | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070155639-A1 | Cleansing bar compositions comprising a high level of water | PROCTER & GAMBLE COMPANY, THE | 2007-07-05 | — | — | US | disclosed |
| US-20070021314-A1 | Cleansing bar compositions comprising a high level of water | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027132-A1 | FRAGRANCE COMPOSITIONS AND USE THEREOF FOR IMPROVING SLEEP | B2M, PER2, CHRM2 | HDAC3 1221/4885HDAC1 2658/4885HDAC2 733/4885 |
| US-12576019-B2 | Personal cleansing composition with an organic acid having a pKa greater than 2.7 | CUTA, SPHK2, SPHK1 | HDAC3 2839/4885HDAC1 1076/4885HDAC2 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.