Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311666 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KMT2ACASP6MAPTCYP3A4 | |
| SCHEMBL20624882 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL6342530 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL28856678 | 0.74 | MEN1 (0.44) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL8282316 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL6304570 | 0.74 | MEN1 (0.32) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL6304569 | 0.74 | MEN1 (0.32) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL16477260 | 0.73 | LMNA (0.42) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL11443275 | 0.73 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1CASP6POLB | |
| SCHEMBL4534380 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1CASP6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849766-B2 | 1,4-diamino-2-alkenylbenzene derivatives, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | AOC1, AOX1, GPX1 | ALDH1A1 5/4885KMT2A 3908/4885MEN1 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.