Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313137 | 1.00 | AKR1B1 (0.64) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL7826031 | 0.90 | AKR1B1 (0.57) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL8085700 | 0.88 | AKR1B1 (0.64) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL16888910 | 0.88 | CA2 (0.54) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL22046126 | 0.86 | CA2 (0.76) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL27687200 | 0.86 | AKR1B1 (0.56) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL11427146 | 0.85 | CA2 (0.56) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL11427147 | 0.85 | CA2 (0.56) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL6295521 | 0.85 | PAM (0.56) | AKR1B1LMNAABCC4GAATSHR | |
| SCHEMBL6295520 | 0.85 | PAM (0.56) | AKR1B1LMNAABCC4GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404221-B2 | Methods of arene alkenylation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-09-02 | — | — | US | disclosed |
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-07-27 | — | — | US | disclosed |
| US-20200385374-A1 | IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF TOLEDO (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200385374-A1 | IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF TOLEDO (US) | 2020-12-10 | — | — | US | disclosed |
| WO-2019036607-A1 | IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF TOLEDO (US) | 2019-02-21 | — | — | WO | disclosed |
| US-6960667-B2 | Fluorescent maleimides and uses thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-01 | — | — | US | disclosed |
| US-20030189191-A1 | Fluorescent maleimides and uses thereof | KUNIMOTO KAZUHIKO (JP) | 2003-10-09 | — | — | US | disclosed |
| US-6508957-B2 | Ultraviolet fluorescent material for void detection and for preparation of scintillators, films, luminescent solar energy collectors, organic electroluminescent devices, printing inks, electrophotographic toners | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-21 | — | — | US | disclosed |
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| US-20020065422-A1 | Fluorescent maleimides and uses thereof | KUNIMOTO KAZUHIKO (JP) | 2002-05-30 | — | — | US | disclosed |
| US-6258954-B1 | ELECTROLUMINESCENCE; DETECTION VOIDS | CIBA SPECIALTY CHEMICALS CORP. | 2001-07-10 | — | — | US | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065422-A1 | Fluorescent maleimides and uses thereof | IK, PAH, MYO1F | AKR1B1 1162/4885LMNA 1976/4885ABCC4 4587/4885 |
| US-20030189191-A1 | Fluorescent maleimides and uses thereof | CBR1, CBR3, MT-CO2 | AKR1B1 2386/4885LMNA 137/4885ABCC4 2576/4885 |
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | CYBB, CBR3, AHR | AKR1B1 280/4885LMNA 1425/4885ABCC4 1685/4885 |
| US-12404221-B2 | Methods of arene alkenylation | CYBB, CBR3, AHR | AKR1B1 280/4885LMNA 1425/4885ABCC4 1685/4885 |
| US-20200385374-A1 | IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME | HDAC1, HDAC8, HDAC2 | AKR1B1 2106/4885LMNA 2343/4885ABCC4 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.