Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 5/20 | 0.41 |
| ▸ | FABP4 | P15090 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717515 | 0.87 | FFAR4 (0.48) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5304037 | 0.86 | PTGDR2 (0.70) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10374308 | 0.84 | PTGDR2 (0.54) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9717536 | 0.82 | FFAR4 (0.44) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4788971 | 0.81 | TSHR (0.55) | PTGDR2ALDH1A1SMN1; SMN2FFAR4TSHR | |
| SCHEMBL9717537 | 0.81 | FFAR4 (0.44) | PTGDR2HPGDALDH1A1FFAR4TSHR | |
| SCHEMBL7292324 | 0.80 | PTGDR2 (0.66) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL19246306 | 0.80 | PTGDR2 (0.66) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7082490 | 0.80 | FFAR4 (0.50) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1300234 | 0.79 | HPGD (0.60) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | PTGDR2 184/4885HPGD 2861/4885ALDH1A1 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.