SCHEMBL9717537

SCHEMBL9717537

O=Cc1ccc(OCCCCCC(=O)O)c(Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.44
PPARA Q07869 3/20 0.42
THRB P10828 2/20 0.41
THRA P10827 1/20 0.41
RAB9A P51151 1/20 0.41
PTGDR2 Q9Y5Y4 3/20 0.41
ALB P02768 1/20 0.40
CNR2 P34972 1/20 0.40
TSHR P16473 1/20 0.39
LTB4R Q15722 2/20 0.39
PPARG P37231 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
NCOA2 Q15596 1/20 0.38
NCOA1 Q15788 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717536 0.99 FFAR4 (0.44) FFAR4PPARATHRBTHRARAB9A
SCHEMBL9717515 0.94 FFAR4 (0.48) FFAR4PPARATHRBTHRARAB9A
SCHEMBL9717613 0.90 PTGDR2 (0.44) FFAR4THRBTHRARAB9APTGDR2
SCHEMBL19025056 0.89 CYSLTR2 (0.43) FFAR4PPARATHRBTHRARAB9A
SCHEMBL6313773 0.81 PTGDR2 (0.53) FFAR4RAB9APTGDR2TSHRALDH1A1
SCHEMBL9721410 0.79 CYSLTR2 (0.41) FFAR4PPARATHRBTHRALTB4R
SCHEMBL9717491 0.79 CYSLTR2 (0.41) FFAR4PPARATHRBTHRALTB4R
SCHEMBL9717485 0.79 CYSLTR2 (0.41) FFAR4PPARATHRBTHRALTB4R
SCHEMBL19246306 0.79 PTGDR2 (0.66) PPARAPTGDR2CNR2LTB4RALDH1A1
SCHEMBL7292324 0.79 PTGDR2 (0.66) PPARAPTGDR2CNR2LTB4RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0240256-B1 COMPOUNDS USEFUL IN TREATING SICKLE CELL ANEMIA MERCK & CO. INC. (US) 1992-04-29 EP disclosed
US-4751244-A NITROALKENYL CARBOXYLIC ACIDS MERCK & CO., INC. (US) 1988-06-14 US disclosed
EP-0240256-A2 Compounds useful in treating sickle cell anemia MERCK & CO. INC. (US) 1987-10-07 EP disclosed