Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717537 | 0.99 | FFAR4 (0.44) | FFAR4PPARARAB9APTGDR2CNR2 | |
| SCHEMBL9717515 | 0.95 | FFAR4 (0.48) | FFAR4PPARARAB9APTGDR2TSHR | |
| SCHEMBL9717613 | 0.91 | PTGDR2 (0.44) | FFAR4RAB9APTGDR2TSHRTHRA | |
| SCHEMBL19025056 | 0.87 | CYSLTR2 (0.43) | FFAR4PPARARAB9APTGDR2CNR2 | |
| SCHEMBL6313773 | 0.82 | PTGDR2 (0.53) | FFAR4RAB9APTGDR2TSHRALDH1A1 | |
| SCHEMBL11684698 | 0.80 | ALDH1A1 (0.43) | PTGDR2TSHRPPARGALDH1A1HPGD | |
| SCHEMBL9717590 | 0.79 | CYSLTR2 (0.40) | FFAR4PPARARAB9ATSHRTHRA | |
| SCHEMBL9717589 | 0.79 | CYSLTR2 (0.40) | FFAR4PPARARAB9ATSHRTHRA | |
| SCHEMBL9717583 | 0.79 | CYSLTR2 (0.40) | FFAR4PPARARAB9ATSHRTHRA | |
| SCHEMBL4094739 | 0.78 | CNR2 (0.57) | FFAR4PPARAPTGDR2CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240256-B1 | COMPOUNDS USEFUL IN TREATING SICKLE CELL ANEMIA | MERCK & CO. INC. (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4751244-A | NITROALKENYL CARBOXYLIC ACIDS | MERCK & CO., INC. (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0240256-A2 | Compounds useful in treating sickle cell anemia | MERCK & CO. INC. (US) | 1987-10-07 | — | — | EP | disclosed |