Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640231 | 0.92 | KDM4E (0.57) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL2734561 | 0.88 | ALDH1A1 (0.78) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL10579016 | 0.86 | KDM4E (0.67) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL29528611 | 0.85 | CNR2 (0.74) | KDM4EMAPTALDH1A1LMNAHPGD | |
| Formaldehyde SCHEMBL27586290 | 0.85 | ALDH1A1 (0.74) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL9457046 | 0.85 | CNR2 (0.74) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL30150496 | 0.85 | KDM4E (0.68) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL28190231 | 0.85 | KDM4E (0.65) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL5662028 | 0.85 | HPGD (0.72) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL7979578 | 0.85 | KDM4E (0.68) | KDM4EMAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1244666-C | Fluorescent maleimides and uses thereof | CIBA SC HOLDING AG (CH) | 2006-03-08 | — | — | CN | disclosed |
| CN-1721498-A | Fluorescent maleimides and uses thereof | CIBA SC HOLDING AG (CH) | 2006-01-18 | — | — | CN | disclosed |
| US-6960667-B2 | Fluorescent maleimides and uses thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-01 | — | — | US | disclosed |
| US-20030189191-A1 | Fluorescent maleimides and uses thereof | KUNIMOTO KAZUHIKO (JP) | 2003-10-09 | — | — | US | disclosed |
| US-6508957-B2 | Ultraviolet fluorescent material for void detection and for preparation of scintillators, films, luminescent solar energy collectors, organic electroluminescent devices, printing inks, electrophotographic toners | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-21 | — | — | US | disclosed |
| CN-1374995-A | Fluorescent maleimides and uses thereof | CIBA SC HOLDING AG (CH) | 2002-10-16 | — | — | CN | disclosed |
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| US-20020065422-A1 | Fluorescent maleimides and uses thereof | KUNIMOTO KAZUHIKO (JP) | 2002-05-30 | — | — | US | disclosed |
| US-6258954-B1 | ELECTROLUMINESCENCE; DETECTION VOIDS | CIBA SPECIALTY CHEMICALS CORP. | 2001-07-10 | — | — | US | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065422-A1 | Fluorescent maleimides and uses thereof | IK, PAH, MYO1F | KDM4E 1873/4885MAPT 1437/4885ALDH1A1 286/4885 |
| US-20030189191-A1 | Fluorescent maleimides and uses thereof | CBR1, CBR3, MT-CO2 | KDM4E 2373/4885MAPT 4621/4885ALDH1A1 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.