Sugi Predict

Sugi Predict / Compounds / Fluacizine

Fluacizine

Fluacizine

SCHEMBL49497

CCN(CC)CCC(=O)N1c2ccccc2Sc2ccc(C(F)(F)F)cc21

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.61
▸ KMT2A Q03164 4/20 0.61
▸ NPSR1 Q6W5P4 2/20 0.60
▸ HPGD P15428 2/20 0.60
▸ GAA P10253 2/20 0.59
▸ HTT P42858 1/20 0.59
▸ KDM4E B2RXH2 2/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ CYP1A2 P05177 2/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ GPR55 Q9Y2T6 1/20 0.53
▸ LMNA P02545 4/20 0.52
▸ TSHR P16473 2/20 0.52
▸ ALOX12 P18054 1/20 0.52
▸ BCHE P06276 2/20 0.51
▸ ACHE P22303 1/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ ABCB11 O95342 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluacizine SCHEMBL29388364 1.00 MEN1 (0.61) MEN1KMT2ANPSR1HPGDGAA
Fluacizine SCHEMBL1650048 0.98 MEN1 (0.59) MEN1KMT2ANPSR1HPGDGAA
Fluacizine SCHEMBL5886152 0.86 TP53 (0.61) MEN1KMT2ANPSR1HPGDGAA
SCHEMBL6313879 0.86 BCHE (0.65) KDM4EALDH1A1CYP2C19TSHRBCHE
Hydrochloric Acid SCHEMBL5499595 0.85 BCHE (0.66) KDM4EALDH1A1CYP2C19LMNATSHR
Chloracyzine SCHEMBL309939 0.83 ALDH1A1 (0.77) MEN1KMT2AKDM4EALDH1A1LMNA
Chloracyzine SCHEMBL29388455 0.83 ALDH1A1 (0.77) MEN1KMT2AKDM4EALDH1A1LMNA
Chloracyzine SCHEMBL30719025 0.83 ALDH1A1 (0.77) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL11622859 0.83 MEN1 (0.67) MEN1KMT2ANPSR1HPGDGAA
Chloracyzine SCHEMBL11614590 0.82 ALDH1A1 (0.79) MEN1KMT2AKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4479032-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS Sage Therapeutics, Inc. (US) 2024-12-25 — — EP claimed
US-20240050442-A1 TRIMEPRAZINE DERIVATIVES AND COMPOSITIONS COMPRISING THE SAME FOR TREATING A NEUROPSYCHIATRIC DISORDER UNIVERSITÉ COTE D'AZUR (FR) 2024-02-15 — — US claimed
US-20230381168-A1 ADJUNCTIVE THERAPY FOR DEPRESSION ANEUROTECH BV (BE) 2023-11-30 — — US claimed
EP-4255437-A1 TRIMEPRAZINE DERIVATIVES AND COMPOSITIONS COMPRISING THE SAME FOR TREATING A NEUROPSYCHIATRIC DISORDER Centre National de la Recherche Scientifique (FR) 2023-10-11 — — EP claimed
WO-2023158668-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS SAGE THERAPEUTICS, INC. (US) 2023-08-24 — — WO claimed
WO-2023159035-A1 NEUROACTIVE STEROIDS FOR TREATMENT OF CNS-RELATED DISORDERS SAGE THERAPEUTICS, INC. (US) 2023-08-24 — — WO claimed
WO-2022122688-A1 TRIMEPRAZINE DERIVATIVES AND COMPOSITIONS COMPRISING THE SAME FOR TREATING A NEUROPSYCHIATRIC DISORDER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-06-16 — — WO claimed
US-20200390698-A1 URETHRAL DEVICES FOR TREATMENT OF PATHOLOGICAL UROLOGICAL CONDITIONS INURA MEDICAL AG (CH) 2020-12-17 — — US claimed
US-20200038420-A1 AMINOSTEROL COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATING DEPRESSION ENTERIN, INC. (US) 2020-02-06 — — US claimed
EP-3411015-A1 URETHRAL DEVICES FOR TREATMENT OF PATHOLOGICAL UROLOGICAL CONDITIONS Inura Medical AG (CH) 2018-12-12 — — EP claimed
US-20040171682-A1 Drugs for chronic pains NICOX S.A. (FR) 2004-09-02 — — US claimed
EP-1438020-A2 TOPICAL COMPOSITIONS AND METHODS FOR TREATING PAIN EpiCept Corporation (US) 2004-07-21 — — EP claimed
WO-2004056305-A2 ADMINISTRATION OF CAPSAICINOIDS ALGORX (US) 2004-07-08 — — WO claimed
EP-1417165-A2 DRUGS FOR CHRONIC PAINS Nicox S.A. (FR) 2004-05-12 — — EP claimed
US-20040076648-A1 Topical compositions and methods for treating pain EPICEPT CORPORATION 2004-04-22 — — US claimed
US-20030082214-A1 Topical compositions and methods for treating pain DISCOVER GROWTH FUND, LLC (VI) 2003-05-01 — — US claimed
WO-2003015699-A2 TOPICAL COMPOSITIONS AND METHODS FOR TREATING PAIN EPICEPT CORPORATION (US) 2003-02-27 — — WO claimed
WO-2003000642-A2 DRUGS FOR CHRONIC PAINS NICOX S.A. (FR) 2003-01-03 — — WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171682-A1 Drugs for chronic pains OPRD1, OPRK1, OPRL1 MEN1 4071/4885KMT2A 1765/4885NPSR1 328/4885
US-20240050442-A1 TRIMEPRAZINE DERIVATIVES AND COMPOSITIONS COMPRISING THE SAME FOR TREATING A NEUROPSYCHIATRIC DISORDER GRIK5, HTR5A, CYP3A5 MEN1 4549/4885KMT2A 240/4885NPSR1 538/4885
US-20200038420-A1 AMINOSTEROL COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATING DEPRESSION HSD17B7, CYP17A1, HSD17B2 MEN1 3448/4885KMT2A 1499/4885NPSR1 218/4885
US-20230381168-A1 ADJUNCTIVE THERAPY FOR DEPRESSION HTR2A, HTR3B, HTR5A MEN1 4844/4885KMT2A 866/4885NPSR1 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.