SCHEMBL631402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL630623	0.83	MAPT (0.52)	MAPTALDH1A1MAPK1TDP1NPC1
	SCHEMBL631175	0.82	ALDH1A1 (0.47)	MAPTALDH1A1MAPK1TDP1NPC1
	SCHEMBL5172935	0.74	ALDH1A1 (0.53)	MAPTALDH1A1TDP1NPC1RAB9A
	SCHEMBL28786813	0.73	MAPT (0.65)	HDAC8HDAC6MAPTALDH1A1MAPK1
	Bicarbonate SCHEMBL3549893	0.72	MAPT (0.60)	HDAC8HDAC6MAPTALDH1A1MAPK1
	SCHEMBL4424762	0.71	HDAC8 (0.77)	HDAC8HDAC6MAPTALDH1A1MAPK1
	SCHEMBL1592539	0.71	MAPT (0.58)	HDAC8HDAC6MAPTALDH1A1MAPK1
	SCHEMBL630966	0.71	MAPT (0.53)	MAPTALDH1A1MAPK1NPC1RAB9A
	SCHEMBL28245577	0.71	HDAC8 (0.71)	HDAC8HDAC6MAPTALDH1A1MAPK1
	SCHEMBL3824666	0.71	GSK3B (0.66)	HDAC8HDAC6MAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.