Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 13/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630049 | 0.90 | KCNQ1 (0.47) | BDKRB1UTS2RKCNQ1YAP1 | |
| SCHEMBL1382749 | 0.90 | KCNQ1 (0.47) | BDKRB1UTS2RKCNQ1YAP1 | |
| SCHEMBL629860 | 0.88 | BDKRB1 (0.41) | BDKRB1KCNQ1YAP1NPSR1 | |
| SCHEMBL631050 | 0.85 | KCNQ1 (0.47) | BDKRB1KCNQ1GAA | |
| SCHEMBL631253 | 0.84 | BDKRB1 (0.42) | BDKRB1KCNQ1 | |
| SCHEMBL631034 | 0.81 | KCNQ1 (0.44) | BDKRB1KCNQ1SMN1; SMN2 | |
| SCHEMBL630823 | 0.80 | KCNQ1 (0.49) | BDKRB1KCNQ1LMNAGAANPSR1 | |
| SCHEMBL631193 | 0.80 | MEN1 (0.47) | BDKRB1KCNQ1SMN1; SMN2 | |
| SCHEMBL630680 | 0.80 | KCNQ1 (0.48) | BDKRB1KCNQ1GAA | |
| SCHEMBL630671 | 0.80 | POLB (0.46) | BDKRB1KCNQ1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |