SCHEMBL6314679

SCHEMBL6314679

Nc1ccc(-c2cccc3ccccc23)c(-c2cccc3ccccc23)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TSHR P16473 1/20 0.47
DHFR P00374 1/20 0.46
MAOA P21397 2/20 0.46
MAOB P27338 1/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
NFE2L2 Q16236 1/20 0.46
DNMT1 P26358 1/20 0.42
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
RGS12 O14924 1/20 0.40
USP2 O75604 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714507 0.88 ALDH1A1 (0.42) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL30302654 0.87 KEAP1 (0.48) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL5187265 0.85 ALDH1A1 (0.50) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL15812930 0.82 ALDH1A1 (0.58) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL30117590 0.82 KEAP1 (0.62) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL788001 0.82 ALDH1A1 (0.56) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL1334192 0.82 KEAP1 (0.62) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL1225129 0.80 ALDH1A1 (0.60) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL4943495 0.80 ALDH1A1 (0.52) KEAP1CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL8107861 0.80 DHFR (0.48) KEAP1CYP3A4ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113165356-B Multilayer sheet and transfer material 哈利玛化成株式会社 2023-12-26 CN disclosed
CN-113165356-A Multilayer sheet and transfer material 哈利玛化成株式会社 2021-07-23 CN disclosed
WO-2020116234-A1 MOLD RESIN WITH ATTACHED HARD COAT LAYER, AND METHOD FOR PRODUCING SAME ハリマ化成株式会社 2020-06-11 WO disclosed
US-6914098-B2 Acrylic elastomer and its composition NIPPON MEKIRON, LIMITED (JP) 2005-07-05 US disclosed
EP-0905163-B1 Acrylic elastomer composition NIPPON MEKTRON KK (JP) 2004-10-27 EP disclosed
US-20040087729-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-05-06 US disclosed
US-20040019154-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-01-29 US disclosed
EP-1171524-A1 THERMOPLASTIC RUBBER COMPOSITION SYH Technologies Pty. Ltd. (AU) 2002-01-16 EP disclosed
US-20010005742-A1 Acrylic elastomer and its composition NIPPON MEKTRON, LIMITED 2001-06-28 US disclosed
EP-1110980-A1 Acrylic elastomer and its composition Nippon Mektron, Limited (JP) 2001-06-27 EP disclosed
WO-2000034383-A1 THERMOPLASTIC RUBBER COMPOSITION SYH TECHNOLOGIES PTY. LTD. (AU) 2000-06-15 WO disclosed
US-6015860-A POLYFUNCTIONAL (BLOCKED) ISOCYANATE, GUANIDINE, QUATERNARY AMMONIUM SALT, TERTIARY AMINE, AND TERTIARY PHOSPHINE VULCANIZATION ACCELERATOR; HEAT AND SCORCH RESISTANCE; RESILIENCE NIPPON MEKTRON, LIMITED (JP) 2000-01-18 US disclosed
EP-0905163-A1 Acrylic elastomer composition Nippon Mektron, Limited (JP) 1999-03-31 EP disclosed