Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249951 | 1.00 | CA1 (0.40) | CA1MAPTCA2GPR84MEN1 | |
| SCHEMBL3365188 | 0.98 | CA1 (0.39) | CA1MAPTCA2GPR84MEN1 | |
| SCHEMBL3245650 | 0.98 | CA1 (0.39) | CA1MAPTCA2GPR84MEN1 | |
| SCHEMBL3246038 | 0.98 | CA1 (0.39) | CA1MAPTCA2GPR84MEN1 | |
| Potassium Ion SCHEMBL3366858 | 0.98 | CA1 (0.39) | CA1MAPTCA2GPR84MEN1 | |
| SCHEMBL5706474 | 0.98 | CA1 (0.41) | CA1MAPTCA2GPR84MEN1 | |
| SCHEMBL3241594 | 0.98 | CA1 (0.39) | CA1MAPTCA2GPR84MEN1 | |
| Lithium Ion SCHEMBL3369017 | 0.98 | CA1 (0.39) | CA1MAPTCA2GPR84MEN1 | |
| SCHEMBL3366160 | 0.98 | CA1 (0.39) | CA1MAPTCA2GPR84MEN1 | |
| SCHEMBL3367432 | 0.98 | CA1 (0.41) | CA1MAPTCA2GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908635-B2 | Flat plate flaking device | CARGILL, INC. (US) | 2005-06-21 | — | — | US | disclosed |
| US-20030039734-A1 | Cooling plates; solidification of fats | HUXEL EDWARD T (US) | 2003-02-27 | — | — | US | disclosed |
| EP-0188318-B1 | DOUGH IMPROVER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0188318-A2 | Dough improver | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4537784-A | COATING LACTIC ACID ONTO CALCIUM LACTATE CARRIERS AND ENCAPSULATING WITH MOLTEN LIPID | SCM CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |
| US-4511584-A | LACTIC ACID PLATED ON CALCIUM LACTATE CARRIER | SCM CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| US-3985913-A | Condiment encapsulation by spray drying | SCM CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3973053-A | Process for tempering beaded fat quickly | SCM CORPORATION (US) | 1976-08-03 | — | — | US | disclosed |
| US-3949094-A | Condiment-treating process and product | SCM CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3949096-A | Spray drying process for encapsulation of condiment particles | SCM CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |