Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310855 | 0.86 | CYP19A1 (0.46) | ALOX15ALDH1A1USP2KMT2AMAPK1 | |
| SCHEMBL6310860 | 0.86 | MAPT (0.46) | ALDH1A1SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL3075817 | 0.85 | ALOX15 (0.48) | ALOX15ALDH1A1KDM4EUSP2NPSR1 | |
| SCHEMBL6310768 | 0.81 | NPY5R (0.49) | ALDH1A1KCNA5L3MBTL1PTGS1 | |
| SCHEMBL3072339 | 0.79 | TSHR (0.47) | ALOX15ALDH1A1KDM4EUSP2NPSR1 | |
| SCHEMBL6308253 | 0.77 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4EUSP2NPSR1 | |
| SCHEMBL3114013 | 0.76 | ALOX15 (0.49) | ALOX15ALDH1A1KDM4EUSP2NPSR1 | |
| SCHEMBL6308259 | 0.75 | ALOX15 (0.53) | ALOX15ALDH1A1KDM4EUSP2NPSR1 | |
| SCHEMBL3078379 | 0.74 | ALDH1A1 (0.53) | ALOX15ALDH1A1KDM4EUSP2NPSR1 | |
| SCHEMBL9875360 | 0.73 | OGG1 (0.54) | ALOX15ALDH1A1KDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | ALOX15 518/4885ALDH1A1 99/4885KDM4E 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.