Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | F9 | P00740 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377736 | 0.85 | KDM1A (0.53) | KDM1AMAOAMAOBRCOR1F10 | |
| SCHEMBL27828556 | 0.81 | KDM1A (0.50) | KDM1AMAOAMAOBRCOR1F10 | |
| SCHEMBL1019042 | 0.80 | ALDH1A1 (0.56) | KDM1AMAOAMAOBRCOR1F10 | |
| SCHEMBL1377738 | 0.79 | KDM1A (0.46) | KDM1AMAOAMAOBRCOR1F10 | |
| SCHEMBL2430289 | 0.79 | L3MBTL1 (0.51) | KDM1AMAOAMAOBRCOR1TNKS | |
| SCHEMBL458678 | 0.79 | KDM1A (0.53) | KDM1AMAOAMAOBRCOR1F10 | |
| SCHEMBL2646792 | 0.78 | KDM1A (0.45) | KDM1AMAOAMAOBRCOR1F10 | |
| Hydrochloric Acid SCHEMBL1950539 | 0.76 | F9 (0.80) | KDM1AMAOAMAOBRCOR1F10 | |
| SCHEMBL1015595 | 0.75 | ALDH1A1 (0.52) | KDM1AMAOAMAOBRCOR1F10 | |
| SCHEMBL2433064 | 0.75 | GSK3B (0.59) | KDM1AMAOAMAOBRCOR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143582-A1 | Method for producing substituted 3-phenylamino-propane-1,2-diols | MERCK PATENT GMBH (DE) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143582-A1 | Method for producing substituted 3-phenylamino-propane-1,2-diols | HPD, PAH, DHPS | F2 463/4885PRSS1 1520/4885PRSS3 2401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.