Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318363 | 1.00 | PPARA (0.39) | PPARAADAMTS5PPARG | |
| SCHEMBL6317694 | 0.82 | PPARA (0.39) | PPARAADAMTS5 | |
| SCHEMBL6320325 | 0.82 | PPARA (0.39) | PPARAADAMTS5 | |
| SCHEMBL6323786 | 0.80 | PPARA (0.37) | PPARAADAMTS5 | |
| SCHEMBL6323783 | 0.80 | PPARA (0.37) | PPARAADAMTS5 | |
| SCHEMBL6325437 | 0.77 | ADAMTS5 (0.39) | PPARAADAMTS5PPARG | |
| SCHEMBL6316934 | 0.77 | PPARA (0.40) | PPARA | |
| SCHEMBL6316940 | 0.77 | PPARA (0.40) | PPARA | |
| SCHEMBL6319916 | 0.76 | PPARA (0.39) | PPARA | |
| SCHEMBL6320732 | 0.76 | PPARA (0.39) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887877-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-05-03 | — | — | US | claimed |
| US-20030229053-A1 | Compounds and methods for the treatment or prevention of flavivirus infections | SHIRE BIOCHEM INC. (CA) | 2003-12-11 | — | — | US | claimed |
| US-20210115003-A1 | NOVEL FULLY SYNTHETIC AND SEMISYNTHETIC PLEUROMUTILIN DERIVATIVES AS NEW ANTIBIOTICS AND THEIR PREPARATION | YALE UNIVERSITY (US) | 2021-04-22 | — | — | US | disclosed |
| US-20190352262-A1 | New Pleuromutilin Antibiotic Compounds, Compositions and Methods of Use and Synthesis | UNIV YALE (US) | 2019-11-21 | — | — | US | disclosed |
| US-6887877-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-05-03 | — | — | US | disclosed |
| US-6875849-B2 | Methods of recovering chaperone proteins and complexes thereof | ARIZONA BOARD OF REGENTS OF BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2005-04-05 | — | — | US | disclosed |
| US-20030229053-A1 | Compounds and methods for the treatment or prevention of flavivirus infections | SHIRE BIOCHEM INC. (CA) | 2003-12-11 | — | — | US | disclosed |
| US-20030031661-A1 | Methods of recovering chaperone proteins and complexes thereof | ARIZONA BOARD OF REGRENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, THE | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190352262-A1 | New Pleuromutilin Antibiotic Compounds, Compositions and Methods of Use and Synthesis | PLEC, MLN, MRPL21 | PPARA 2994/4885ADAMTS5 3403/4885PPARG 3691/4885 |
| US-20210115003-A1 | NOVEL FULLY SYNTHETIC AND SEMISYNTHETIC PLEUROMUTILIN DERIVATIVES AS NEW ANTIBIOTICS AND THEIR PREPARATION | PLEC, MRPL21, VIP | PPARA 2903/4885ADAMTS5 2108/4885PPARG 2971/4885 |
| US-20030229053-A1 | Compounds and methods for the treatment or prevention of flavivirus infections | HAVCR2, ZC3HAV1, MAVS | PPARA 2311/4885ADAMTS5 1548/4885PPARG 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.