Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 16/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631792 | 0.79 | RBP4 (0.52) | RBP4POLBMEN1KMT2ANPSR1 | |
| SCHEMBL3792498 | 0.74 | RBP4 (0.53) | RBP4POLBMEN1KMT2ANPSR1 | |
| SCHEMBL630839 | 0.73 | RBP4 (0.75) | RBP4ALDH1A1 | |
| SCHEMBL766323 | 0.72 | RBP4 (0.87) | RBP4POLBMEN1KMT2ANPSR1 | |
| SCHEMBL3718602 | 0.71 | RBP4 (0.72) | RBP4POLBMEN1KMT2ANPSR1 | |
| SCHEMBL630593 | 0.71 | RBP4 (0.61) | RBP4LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27873708 | 0.70 | RBP4 (0.80) | RBP4POLBMEN1KMT2ANPSR1 | |
| SCHEMBL3718601 | 0.70 | RBP4 (0.69) | RBP4POLBMEN1KMT2ANPSR1 | |
| SCHEMBL766086 | 0.69 | L3MBTL1 (0.64) | RBP4 | |
| SCHEMBL631197 | 0.69 | RBP4 (0.69) | RBP4SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |