Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PREP | P48147 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758726 | 1.00 | CTRB1 (0.66) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL8426716 | 0.88 | NPSR1 (0.68) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL26477642 | 0.88 | NPSR1 (0.68) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL8428146 | 0.88 | NPSR1 (0.68) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL953204 | 0.86 | KMT2A (0.69) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL7126774 | 0.86 | CTRB1 (0.65) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL7265745 | 0.86 | KDM4E (0.78) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL953206 | 0.86 | KMT2A (0.69) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL7122529 | 0.86 | CTRB1 (0.65) | CTRB1NPSR1KDM1ARCOR1TSHR | |
| SCHEMBL7265734 | 0.86 | KDM4E (0.78) | CTRB1NPSR1KDM1ARCOR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-05-11 | — | — | US | disclosed |
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-05-11 | — | — | US | disclosed |
| US-20050153951-A1 | Neurotrophic pyrrolidines and piperidines, and related compositions and methods | KANOJIA RAMESH M (US) | 2005-07-14 | — | — | US | disclosed |
| EP-1202990-A2 | NEUROTROPHIC PYRROLIDINES AND PIPERIDINES, AND RELATED COMPOSITIONS CONTAINING THEM | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001004116-A2 | NEUROTROPHIC PYRROLIDINES AND PIPERIDINES, AND RELATED COMPOSITIONS CONTAINING THEM | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |
| EP-0475184-B1 | Process for the production of peptides by solid phase synthesis | HOECHST AG (DE) | 1995-02-08 | — | — | EP | disclosed |
| EP-0475184-A1 | Process for the production of peptides by solid phase synthesis | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | BET1, PRR12, PREP | CTRB1 3471/4885NPSR1 3004/4885KDM1A 1047/4885 |
| US-20050153951-A1 | Neurotrophic pyrrolidines and piperidines, and related compositions and methods | BDNF, NTRK2, NGF | CTRB1 3866/4885NPSR1 32/4885KDM1A 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.