Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318069 | 0.80 | KDR (0.39) | KMT2ASMN1; SMN2KDM4EKDRNOTUM | |
| SCHEMBL6325841 | 0.72 | MAPT (0.32) | KDM4E | |
| SCHEMBL6318837 | 0.69 | KDR (0.36) | KMT2ASMN1; SMN2KDRNOTUMMGAM | |
| SCHEMBL6325319 | 0.66 | KDR (0.44) | KMT2ASMN1; SMN2KDM4EKDRNOTUM | |
| SCHEMBL16836398 | 0.64 | TLR8 (0.55) | KMT2ASMN1; SMN2KDM4ECHRNB2CHRNA4 | |
| SCHEMBL6317920 | 0.64 | CHRNB2 (0.36) | KMT2ASMN1; SMN2KDM4EKDRNOTUM | |
| SCHEMBL6317918 | 0.62 | CHRNB2 (0.34) | KMT2ASMN1; SMN2KDM4EKDRNOTUM | |
| SCHEMBL18260414 | 0.61 | TLR8 (0.58) | KMT2ASMN1; SMN2KDM4ECHRNB2CHRNA4 | |
| SCHEMBL11048321 | 0.61 | CYP1A2 (0.48) | KMT2ASMN1; SMN2KDM4ECHRNB2CHRNA4 | |
| SCHEMBL18260416 | 0.61 | TLR8 (0.58) | KMT2ASMN1; SMN2KDM4ECHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | KMT2A 2953/4885SMN1; SMN2 4738/4885KDM4E 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.